Las Vegas cultivators have quietly built a terroir of their own, and few outfits are more “Vegas” than Medizin, Planet 13’s in-house grow. Their signature sativa Chloe—created by Medizin’s Chris Wren—has long been a hometown favorite for its energetic lift and spice-sweet nose. You’ll also see classic house cuts like Banana OG and Mango Kush on the Planet 13 menu, typically in fresh pre-packs that move fast. Shop it at the Planet 13 SuperStore, the just-off-Strip mega-dispensary that’s open 24/7.

If you’re chasing terp-heavy exotics, The Grower Circle (TGC) is a Vegas craft darling with small-batch drops that sell out on weekends. Recent appearances include Zosa, Double Down, Sour Gak, and even single-strain infused pre-rolls—usually posted to Planet 13’s live menu when they land. Expect dense structure, loud candy-gas profiles, and tidy trim that preserves volatile terps. Find TGC items at Planet 13; check the brand tile to see what’s in right now.

Another homegrown heavyweight, Nature’s Chemistry, has built a reputation for clean, consistent flower and solventless drops. On the Strip, look for NC OMG, Gush Mintz, Garlic Cocktail or live rosin disposables like Cosmic Mintz—all of which rotate through Planet 13’s menu. NC’s own materials underline a quality-first process; in practice, you get bright jar appeal and steady potency across lots.

For a true Strip stop, Thrive Cannabis Marketplace (The Strip) curates a strong lineup from Matrix NV, a long-running Las Vegas cultivator with citrusy sativas and dessert-leaning hybrids. Watch for Clementine (Tangie × Lemon Skunk), Drama Queen (aka Dream Queen), and Mendo Breath (Mendo Montage × OGKB). Thrive’s Strip shop sits by Resorts World and runs 24 hours, making it an easy late-night pickup before or after a show.

Rounding out the locals column, Tryke—the cultivation behind the Reef legacy—remains embedded at Curaleaf Las Vegas Strip (formerly Reef) on Western Ave, a short hop off Las Vegas Blvd. Expect steady deals on Tryke pre-rolls and flower (Primus pops up regularly), with frequent promos that make it a value play for tourists and night-shift hospitality folks alike.

And don’t sleep on Vegas Valley Growers (VVG) for a truly Vegas-born brand. Their Dosi Face, Frosted Sapphire, and MAC-1 prerolled options have been showing on Planet 13’s menu—great for quick, terp-rich sessions without the grind and roll. It’s a handy add-on if you’re already grabbing Medizin or TGC.

Quick Where-to-Buy (Strip & Strip-adjacent)

• Planet 13 SuperStore (near Strip): Medizin, The Grower Circle, Nature’s Chemistry, VVG.
• Thrive – Las Vegas Strip (2975 S Sammy Davis Jr Dr): Matrix NV (Clementine, Drama/Dream Queen, Mendo Breath).
• Curaleaf – Las Vegas Strip (formerly Reef, 3400 Western Ave): Tryke flower & pre-rolls (frequent promos).

Menus change daily—always peek at live menus before you Uber over.

Learn More: Identifying High-Quality Cannabis Flower from Reputable Cultivators